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Catalpol

Product Name
Catalpol
CAS No.
2415-24-9
Chemical Name
Catalpol
Synonyms
CATAPOL;CATALPOL;catalpinoside;Catapol ,>=98%;Catalpol,Catalnol;Catalpol 2415-24-9;CATALPOL WITH HPLC;,6-beta,6a-alpha))-;Catalpol, ≥97%(HPLC);Digitalis purpurea L
CBNumber
CB6127844
Molecular Formula
C15H22O10
Formula Weight
362.33
MOL File
2415-24-9.mol
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Catalpol Property

Melting point:
203-205°C
Boiling point:
675.6±55.0 °C(Predicted)
Density 
1.72±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
pka
12.79±0.70(Predicted)
color 
White to Off-White
InChIKey
LHDWRKICQLTVDL-CLLMHHLUSA-N
LogP
-4.609 (est)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
LZ5776816
HS Code 
29389090
Toxicity
mouse,LD,intravenous,> 2500mg/kg (2500mg/kg),Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64, Pg. 93, 1968.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89595
Product name
Catalpol
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$521
Updated
2024/03/01
Sigma-Aldrich
Product number
50839
Product name
Catalpol
Purity
≥96% (HPLC)
Packaging
25mg
Price
$306
Updated
2024/03/01
Cayman Chemical
Product number
24925
Product name
Catalpol
Purity
≥98%
Packaging
50mg
Price
$60
Updated
2024/03/01
Cayman Chemical
Product number
24925
Product name
Catalpol
Purity
≥98%
Packaging
100mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
24925
Product name
Catalpol
Purity
≥98%
Packaging
250mg
Price
$201
Updated
2024/03/01
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Catalpol Chemical Properties,Usage,Production

Description

Catalpol is an iridoid glycoside that has been isolated from R. glutinosa and has diverse biological activities, including anti-apoptotic, pro-angiogenic, and radioprotective properties. It protects against mitochondrial pathway-dependent apoptosis in PC12 rat adrenal pheochromocytoma cells and H9c2 rat embryonic ventricular myocardial cells when used at a concentration of 10 μM. Catalpol pretreatment reduces apoptosis and improves viability in AHH-1 human lymphocyte cells exposed to ionizing radiation and reduces intestinal damage induced by radiation in mice when used at concentrations and doses ranging from of 25 to 100 μg/ml and 25 to 100 mg/kg, respectively. In a rat model of stroke, catalpol (5 mg/kg, i.p.) increases the expression of erythropoietin and VEGF and improves angiogenesis in the brain.

Chemical Properties

Light brown powder

Uses

Catapol is an iridoid glucoside that has been shown to alleviate neuropathic pain.

Definition

ChEBI: Catalpol is an organic molecular entity. It has a role as a metabolite.

Catalpol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Catalpol manufacturers

ANHUI WITOP BIOTECH CO., LTD
Product
Catalpol 2415-24-9
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10 tons
Release date
2021-03-19
Shanghai Chinqesen Biotechnology Co., Ltd.
Product
Catalpol 2415-24-9
Price
US $20.00-10.00/BOX
Min. Order
10BOX
Purity
99
Supply Ability
20TONS
Release date
2023-11-01
Henan Fengda Chemical Co., Ltd
Product
Catalpol 2415-24-9
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-27

2415-24-9, CatalpolRelated Search:


  • CATALPOL
  • CATAPOL
  • ,6-beta,6a-alpha))-
  • beta-d-glucopyranoside,1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)
  • catalpinoside
  • de(p-hydroxybenzoyl)catalposide
  • des-p-hydroxybenzoyl-catalposid
  • oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl,(1as-(1a-alpha,1b-beta,2-beta,5a-beta
  • Catalpol 2415-24-9
  • Catalpol, ≥97%(HPLC)
  • [1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6a.alpha.)]-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-beta-D-glucopyranoside
  • .beta.-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno4,5cyclopenta1,2-cpyran-2-yl
  • CATALPOL WITH HPLC
  • 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
  • β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-
  • Catalpol,Catalnol
  • [(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside
  • Catapol ,>=98%
  • (1AS-(1aα,1bβ,2β,5aβ,6β,6aα-))1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxyMethyl)oxireno(4,5)cyclopenta(1,2-c)-pyran-2-yl-beta-D-glucopyranoside
  • (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside
  • Digitalis purpurea L
  • (3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
  • (2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,5a,6,6a-tetrahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
  • (2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • (2S, 3R, 4S, 5S, 6R) -2- (((1aS, 1bS, 2S, 5aR, 6S, 6aS) -6-hydroxy-1a - (hydroxymethyl) -1a, 1b, 2,5a, 6,6a - hexahydroepoxyethano [2 ', 3': 4,5] cyclopentadieno [1,2-c] pyran-2-yl) oxy) -6- (hydroxymethyl) tetrahydro-2H-pyran-3,4,5-triol
  • (2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • 2415-24-9
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors
  • Iridoids